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Further emphasizing their role as signaling molecules, ROS and particularly H 2 O 2 , are also major regulators of gene expression, as evidenced by extensive genome expression reprogramming under conditions promoting H 2 O 2 accumulation (Queval et al., 2007

Heterophyllin B inhibited TGF-1 and Smad2/3 phosphorylation, and reduced myofibroblast markers -SMA and COL-1 in lung tissues, demonstrating anti-pulmonary fibrosis effects

Volcano plot screening showed that the ribosomal protein RPL15 significantly decreased after GGT knockout

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Risks include thyroid C-cell tumors (contraindicated with personal/family MTC or MEN2)496903084605990312L22-L26, pancreatitis, gallbladder disease, and hypoglycemia when combined with insulin496903084605990312L206-L209