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Other outbreaks have been linked to aerosol (mist) sources in the community or with cruise ships and hotels, with the most likely sources being hot tubs, cooling towers (air-conditioning units from large buildings), and water used for drinking and showering. To prevent the build up of the Legionella bacteria, Occupational Safety & Health Administration (OSHA) recommends that water systems be properly inspected and maintained with frequent flushing of domestic water systems at very high temperatures

A small miscalculation here can cascade into skewed results, wasted materials, and compromised research integrity

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Therefore, although the drug concentration was significantly higher in micelle-injected mice compared to commercial itraconazole injection, the greater antifungal efficacy of the micelle formulation due to higher extent of brain drug delivery cannot be concluded