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As histone acetylation is reversible, and brain development continues after birth, treatments that address deficits in histone acetylation may ameliorate the condition

NbClust: an R package for determining the relevant number of clusters in a data set

Since the developing nervous system and its critical processes rely heavily on the ATP produced by OXPHOS in the mitochondria, the immature brain is critically vulnerable to faults in energy supply [34, 35]