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An example of an approved therapy is Venetoclax, a BCL2 inhibitor which has demonstrated efficacy as a monotherapy or in combination regimens for treating chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML) (1517)

10.1016/S0735-1097(02)02866-8 35 KumarA.PalfreyH

These are seven transmembrane-spanning proteins belonging to the G-protein-coupled receptor (GPCR) superfamily, by the cytosolic enzyme quinone reductase (QR2) [7] [Figure 2]