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In Figure 1 is reported a simplified schema of these two main branches of the non-protein TRP metabolism in humans, also showing their interplays with energy metabolism (KYN paths), neurotransmission/inflammation (5-HT and KYN path in opposite direction) and circadian pacemakers (MLT)

for 5 days) was reported to attenuate diethylnitrosamine (DENA)-induced liver carcinogenesis and reduce serum AFP and VEGF levels and liver HGF protein in rats [94]

These two factors may depend on selected localization of the affinity tags on the capsid: to which proteins the tags are fused and in what position