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Previously, we established a connection between taurine and ER stress, with increasing evidence showing that dietary taurine helps reduce hepatic inflammation and ER stress induced by high dietary carbohydrate intake [120]

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Ann Saudi Med 2011;31:3-13

Autophagy-lysosomal biogenesis is tightly regulated by TFEB, which can be deacetylated by SIRT1 and activate the expression of several downstream autophagy-associated genes, such as LAMP1 (lysosomal associated membrane protein 1), LAMP2 (lysosomal associated membrane protein 2) and CTSD (cathepsin D) [42, 43]

Several key enzymes, including CYP3A4, CYP19A1, CYP2E1, TNF, BCL-2, RYR2, and ATP2A1, were identified as potential targets underlying the anti-chemotherapy-related fatigue effect of AC (Zhang et al