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DOI: Subramani, C., Rajakkannu, A., Rathinam, A., Gaidhani, S., Raju, J., & Singh, D

Neuron 30 (3), 665676

All these data support that MCJ is a downstream target gene under the transcriptional regulation of HIF2

This injury extends beyond the local gut, as the disruption of the intestinal mucosal barrier facilitates bacterial and endotoxin translocation into the systemic circulation, triggering a systemic inflammatory response that can progress to sepsis and multiple organ dysfunction syndrome (MODS)