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In some embodiments, a lipid formulation featured in the invention can be used to modify target gene expression in a tumor cell line, including but not limited to HeLa, HCT116, A375, MCF7, B16F10, Hep3b, HUH7, HepG2, Skov3, U87, and PC3 cell lines

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ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organsthreshold doses for tissue reactions in a radiation protection context