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For patients with diabetes, glucose control is especially important because high blood sugar can slow immune response and wound repair

Murine macrophage RAW264.7 and human monocyte U937 cells were treated with BBR and heat killed S

doi: 10.1016/j.biopha.2020.110949

Using both is redundant rather than synergistic and may cause NAD+ oversupply, which preliminary research suggests could impair SIRT1 regulation

For example, a phase I clinical study revealed that ascorbate concentrations could safely reach 25-30 mM with intravenous infusion of 100 g of vitamin C