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Gonsalves N, Doerfler B, Zalewski A, Yang GY, Martin LJ, Zhang X et al

Methods 39 , 175191

TRAF3, a key member of this family, is frequently suppressed in glioblastoma (GBM) due to promoter hypermethylation

Experiments need to be designed where the inhibitors/activators of the identified genes are administered simultaneously with various ASMs to evaluate the effects of their co-treatment

Although hardly detectable in tissue, expression and activation of the matrix metalloproteases (MMPs) begins upon injury of the nervous system (Shubayev et al., 2006