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S32, HSP90 was significantly upregulated in the ZFPG, ZFP + US, and ZFPG + US groups (increased by 10.27, 13.37, and 19.12 folds, respectively), ascribed to the ZFPG-mediated enhanced thermal damage and oxidative stress from US cavitation

In contrast, fluoxetine, a widely prescribed selective serotonin reuptake inhibitor (SSRI) for depression, is associated with an increased incidence of metabolic conditions like NAFLD (291, 292)

10.1016/j.phymed.2020.153405 163 MenziesF

Notably, patients with RA combined with T2DM exhibit more pronounced dyslipidemia and glucose metabolism disorders, characterized by greater insulin resistance, elevated baseline inflammation levels, and more severe lipid profile abnormalities