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We propose two non-mutally exclusive mechanisms for this improved ANT function: direct interaction with the ANT protein and modification of ANT PTMs

Functional complex II and GPDH are sufficient for ubidecarenone-induced ROS production and cell death As BPM31510 treatment affects the Q-pool between Complexes II and III, its effect in Rho0 cells was examined

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The activation of YAP subsequently induces extracellular matrix (ECM) deposition through enhanced secretion of connective tissue growth factor (CTGF), while concurrently promoting the production of fibrous collagen and connective tissue by the surrounding fibroblasts