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Also, pyruvate dehydrogenase kinase isoenzyme-4 encodes pyruvate dehydrogenase complex (PDK)

Steroidal saponins, found in many adaptogenic plants, have been shown to promote neuroplasticity/neurogenesis, restore neurotransmitter function, enhance key neuroprotective compounds like BDNF, and exert a protective effect over the HPA-axis

Research suggests it has a relatively mild safety profile, but long-term safety studies are still limited

Ascorbic acid (vitamin C) and -tocopherol (vitamin E) obtained mostly from diet are also important non-enzymatic erythrocyte antioxidants [19]