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After getting a B12 shot, you should watch out for these symptoms and see a doctor if you have: Strong pain where you got the shot Some stomach upset Feeling swollen Skin feeling itchy for a while In really rare cases, there might be more serious risks like: A severe allergic reaction called anaphylaxis Fluid build-up in the lungs Heart problems Blood clots in the bodys blood vessels A type of blood cancer, called polycythemia vera

Patients with systemic inflammation that disrupts multiple body systems

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While any intramuscular injection can cause some pain, the middle deltoid is generally well-tolerated due to its muscle density and lower risk of irritation

Box plots indicating the median (center line), interquartile range (IQR) (box bounds, 25th and 75th percentiles) and smallest and largest values within 1.5 IQR (whiskers) ( a-e )