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These effects, as well as downregulation of PPAR and C/EBP (which facilitate the transcription of various pre-adipogenic genes), inhibit adipogenic differentiation and intracellular lipid amassing in cultured 3T3-L1 preadipocytes (Jung et al., 2019)

It defines the pace of aging by controlling how effectively cells detoxify, how efficiently mitochondria produce energy, and how well the body withstands the cumulative stress of time."