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doi: 10.1186/s12935-023-02848-3

ROS directly oxidize the glutaminase protein, altering its structure and function, and modulating metabolic pathways, including elevated mitochondrial ROS production, which further affects glutaminase activity

A similar result was found in mice challenged with B16-F10 cells (Supplementary Fig

Nikolich-Zugich J, Knox KS, Rios CT, Natt B, Bhattacharya D, Fain MJ (2020) SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes