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The standard regimen is 1 mg administered three times weekly for two weeks (or on alternate days for six doses if neurological symptoms are present), followed by maintenance doses every two to three months

Vitamin B12 is a nutrient that provides supplements to the body to keep your blood and nerve cells healthy while aiding to make DNA, which is the genetic material in all of your cells

NSAIDs reduce inflammation by blocking certain enzymes, which helps with pain but doesnt address the underlying tissue damage

Moll S et al

The problem is that the crystals are often extensive, and track back to the bone, so there is not a good healing surface once the tophus is removed