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coli proB , and the resulting strains were W303-1b/gsh1 ( GSH1 deletion), W303-1b/gsh1/pro1 ( GSH1::P gap - PRO1 - T pgk1 ) and W303-1b/gsh1/proB ( GSH1::P gap - proB - T pgk1 ) (Table 2)

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Mice lacking one of the alleles of the COQ7 gene ( mCOQ7/mCLK1 gene ) show extended longevity even though their CoQ levels are the same as wild-type mice, suggesting that a factor other than CoQ per se may be responsible for lifespan extension in these animals (Lapointe and Hekimi, 2008)