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These characteristics contribute to enhanced colloidal stability, prolonging the NPs' half-life in the systemic circulation, reticuloendothelial (RES) system clearance, and promoting passive accumulation of the NPs within tumor tissue 41

That is why its effect in studies extends far beyond the gastrointestinal tract, where it was originally discovered

& He, X.-X

This finding is consistent with a study that found low-dose lithium to stabilize patients with Alzheimer's disease

whether contrast-induced oxidative stress acts as a direct trigger, or if other intermediates (e.g., endoplasmic reticulum stress and mitochondrial dysfunction) are involved, requires definitive validation