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HCC HCC is a leading cause of global cancer mortality, often associated with CLD and characterized by late diagnosis, high recurrence, and poor survival 93,94,95,96

Basal blood hematology and biochemistry were performed at the screening Visit 1 on all subjects

Annual review of pharmacology and toxicology [J], 2005 (45): 51-88

Vascular SMCs have been found to contribute to atherosclerotic plaque formation through proliferation, migration, and apoptosis, and they are involved in inflammation, extracellular matrix synthesis, and foam cell formation through cholesterol uptake [50]