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Chemical characterization and biological activity of Chaga ( Inonotus obliquus ), a medicinal mushroom

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Asian Pac J Cancer Prev 16(12):49934996 Wheate NJ, Walker S, Craig GE, Oun R (2010) The status of platinum anticancer drugs in the clinic and in clinical trials

In native physiology, the six IGFBPs perform several overlapping regulatory jobs: they extend the circulating half-life of IGF-1, they create a reservoir of hormone that can be released as needed, they modulate the amount of free peptide available to receptors, and in some contexts they exert IGF-independent effects of their own

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