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Absorbance at 490 nm was measured using a Synergy H1 BioTek (Agilent) spectrophotometer after a 3-hour dark incubation of cells with the reagent

This naturally occurring copper peptide plays an important role in tissue repair, inflammation regulation, and cellular health, making it valuable not only for appearance-focused goals, but also for recovery and long-term wellness

Barrier Function The stratum corneum the outermost skin barrier benefits from copper peptide-induced improvements in lipid synthesis

In both in vitro and in vivo models, the study reported that GHK-Cu reduced the production of TNF- and IL-6 through the suppression of NFB p65 and p38 mitogen-activated protein kinase (MAPK) signaling

In the REDEFINE 1 trial, only 1% of participants discontinued treatment due to adverse events