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The nasal mucosa provides a rich blood supply, a large surface area of approximately 150 square centimeters, and direct access to systemic circulation without hepatic first-pass metabolism

This prevents swelling and bruising and helps spread the medication Stand up

Simeone G, Bergamini M, Verga MC, Cuomo B, D'Antonio G, Iacono ID, Mauro DD, Mauro FD, Mauro GD, Leonardi L, Miniello VL, Palma F, Scotese I, Tezza G, Vania A, Caroli M