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As a result, myocardial fibrosis, inflammation, and apoptosis were markedly attenuated, accompanied by improvements in mitochondrial function and calcium homeostasis ( At the in vitro cellular level, numerous studies have employed high-glucose or high-lipid-induced cardiomyocyte models to examine how 4-HNE dysregulation affects cardiomyocyte function, further substantiating its pathogenic role in DCM

Subsequently, we found that the serum L-Gln concentration in the rats of the OA group was significantly lower than that in the rats of the sham group ( P = 0.0062)

Nakhaee, S., Dastjerdi, M., Roumi, H., Mehrpour, O

The revision would align the text of this section with our adoption of the APP Plus quality measure set for performance year 2025 and subsequent performance years