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In addition, the involvement of neurofibromin in the RAS-MAPK pathway may interfere with cell proliferation and differentiation and, therefore, increase the predisposition to development of malignant tumors in these patients

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In this study, our results have revealed an unexplored link between gankyrin and p53, which plays a role in suppressing ferroptosis in TNBC cells

Kiewhuo K, Gogoi D, Mahanta HJ, Rawal RK, Das D, Sastry GN (2022) North East India medicinal plants database (NEI-MPDB)

Decreasing glutathione levels in smt15-1 strain restores its cell-size defect Because elevated glutathione content is co-segregated with the small cell-size of smt15-1 (Fang et al., 2014), we were interested in testing whether the increased glutathione caused increased cell division number and therefore generation of small sized daughters in the smt15-1 mutant