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Description

S.CoimbraL

First, we generalize the compelling influence of HGF/c-MET pathway on multiple cellular processes

The cytoplasmic tyrosine phosphorylation (P) sites of the c-Met are indicated: Tyr1003 is in the juxtamembrane binding site, Tyr1234 and Tyr1235 are in the active site of the kinase and Tyr1349 and Tyr1356 are in the bidentate docking site (Fig