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It has also been observed a correlation between high levels of GSTP1-1 in the brain and medical intractability, suggesting that the enzyme may contribute to resistance to antiepileptic drug treatment 62

Furthermore, in keeping with observations in rodent skeletal muscle and liver [112,113], -S182/4 has by far the highest phospho-stoichiometry under basal conditions, in some instances approximating 100% for 1-containing AMPK