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[37] [38] The evolution of NiSOD is currently predicted to have occurred around the time of the GOE when a decrease in aquatic bioavailability of Fe took place

An intestinal microbiota-farnesoid X receptor axis modulates metabolic disease

developed a new series of indole/indazole-piperazine pyrimidine analogs with neuroprotective properties (97)

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this occurs because there is not enough vitamin B12 in the diet, or poor absorption Pernicious anemiaa type of megaloblastic anemia caused by a lack of intrinsic factor, so that vitamin B12 is not absorbed Fatigue, weakness Nerve damage with numbness, tingling in the hands and legs Memory loss, confusion Dementia Depression Seizures Up to 15% of the general population has a B12 deficiency