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Through autocrine and paracrine binding to IL-1 receptors, it intensifies inflammatory signaling and promotes the expression of cytokines such as TNF- and IL-6, as well as chemokines including CXCL1 and IL-8

Clinical drug investigation 34 , 4352, (2014)

Supports healthy peripheral nerve function

GLP-1 agonists reduce appetite primarily through central nervous system pathways, while amylin analogues act through separate but overlapping mechanisms, slowing gastric emptying and suppressing glucagon secretion

Before formal analysis, the normality and homogeneity of variance were verified using the Shapiro-Wilk test and Levenes test, respectively