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Genetic susceptibility of term pregnant women to oxidative damage

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Studies have demonstrated significantly lower plasma antioxidant concentrations, higher oxidative stress biomarkers, and more mitochondrial morphologic abnormalities in tissue biopsies of patients with neurodegenerative diseases (Bourdel-Marchasson et al., 2001

However, the dual role of IL-2 in supporting both effector T cells and regulatory T cells poses a potential limitation, as IL-2-driven regulatory T cell expansion could suppress antitumor immunity