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1B), and then maintained for 5 days in OL differentiation medium (DM) containing DMEM (Thermo Fisher), 1% P/S (Thermo Fisher), 1 mM sodium pyruvate (Sigma), 0.1% bovine serum albumin (Sigma), 50 g/ml apotransferrin (Sigma-Aldrich), 5 g/ml insulin (Sigma-Aldrich), 30 nM sodium selenite (Sigma), 10 nM biotin (Sigma-Aldrich), 10 nM hydrocortisone (Sigma-Aldrich a), 15 nM triiodothyronine (Sigma), 10 ng/ml ciliary neurotrophic factor (Cell Guidance Systems), and 5 g/ml N-acetyl-cysteine (Sigma-Aldrich)

R -ALA was synthesized through the resolution of racemic ALA by enzymatic esterification of the carboxylic group, which consists of four carbon atoms away from the stereogenic center (Scheme 21)

Metabolite signature associated with stress susceptibility in socially defeated mice

By preventing this damage, glutathione preserves cellular NAD+ pools

The gut microbiota and its implication in the development of atherosclerosis and related cardiovascular diseases