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Since the accumulation of uremic toxins in CKD patients engenders various neurological complications, treatments that target the significant reduction of these metabolites not only significantly delay CKD progression but also greatly improve cognitive function in these patients (Faucher et al., 2023)

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Finally, from the perspectives of promotion, inhibition, transformation, and common upstream molecules, we summarized the crosstalk among apoptosis, autophagy, and ferroptosis in the context of ROS

and 8 = a larger ulcer (6 mm)

Systemic anti-inflammatory signaling: TB-500 downregulates inflammatory cytokines across multiple tissue types, including muscle, tendon, cardiac, and neural tissue