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Severe congenital disabilities can occur with Accutane usage during pregnancy, including: Hearing and visual impairment Missing or malformed earlobes Brain function abnormalities Facial dysmorphisms, such as small or missing eyes or a cleft palate Congenital heart defects Hydrocephalus (fluid and pressure buildup on the brain) Any patient who can become pregnant must use two effective forms of birth control during treatment or commit to abstinence

Generic Labeling Conventions Generic vitamin B12 supplements follow standard names

Silverman JL, Oliver CF, Karras MN, Gastrell PT, Crawley JN (2013) AMPAKINE enhancement of social interaction in the BTBR mouse model of autism

PPAR agonist rosiglitazone suppresses renal mPGES-1/PGE2 pathway in db/db mice