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Tanji K, Maruyama A, Odagiri S, Mori F, Itoh K, Kakita A, et al

Both homocysteine and its reactive metabolite, homocysteine thiolactone, can damage blood vessels and other tissues, and even levels in the upper normal range are associated with increased allcause mortality Genetic variants can increase the risk of high homocysteine, depending on your intake of B vitamins and choline