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Additionally, other TrxR inhibitors, such as Curcumin, have been associated with perturbations in the autophagy-lysosomal degradation pathway 90 and can reduce GPX4 and FSP1 protein levels 91,92

Histopathological analysis of rat SNpc region showed the mild formation of LD in the RT group

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Therapeutic targeting of Cx43 hemichannels Targeting astrocyte connexin hemichannels has disease-modifying effects in various neurological diseases (Fig