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However, the F-statistic prioritizes sites with large overall DNAm differences across all cell types, which can lead to the over-selection of CpGs that strongly differentiate one or a few cell types while neglecting others, resulting in imbalanced discriminatory power within the panel

33 Another mechanism of bacterial drug resistance is reduced permeability, which prevents the entry of drugs

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[DOI] [PMC free article] [PubMed] [Google Scholar] 259

This breakthrough, published May 2, 2024, in Cell , appears to overcome difficulties that have long frustrated previous attempts to reverse a form of nerve damage that robs people with MS of motor control and gradually blunts cognitive functions for many people as they age