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Therefore, to identify the role of NF-B and the regulative mechanism between GPX1 and NF-B in SGNs damage induced by peroxynitrite, we measured the NF-B pathway in SGNs after peroxynitrite administration with GPX1 upregulation or deficiency (Figure 8A)

This, in turn, prompts the anterior pituitary to secrete adrenocorticotropic hormone (ACTH), which ultimately triggers the release of cortisol from the adrenal cortex

2023;12:190 Multidisciplinary Digital Publishing Institute