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These rings are connected by a seven-carbon chain that includes two carbonyl groups located at positions 3 and 5 (commonly referred to as the -diketone moiety), which can undergo keto-enol tautomerism [14] (Figure 1)

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Further studies are needed to fully understand the complex mechanisms of oxidative stress and its role in the pathogenesis of TAO

Antioxidant action reduces oxidative stress, neutralizes free radicals, and protects mitochondria

Bacterial strains and culture Lactobacillus murinus freeze-dried powder (BeNa Culture Collection, Beijing, China) was dissolved in 25 ml of MRS broth (Hope Bio-Technology, Qingdao, China)