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Acknowledgements This work was supported by grants from the Swedish Cancer Fund (Cancerfonden), the Swedish Research Council (VR), Radiumhemmets Forskningsfonder and Karolinska Institutet

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At 12 h post-injection, mice administered BEAGA/ApoE-PDHD showed much stronger ICG fluorescence in glioma than that injected with ApoE-PDHD, while mice receiving BEAGA-PDHD injection showed no detectable ICG fluorescence in tumor site (Supplementary Fig