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LCN2, an acute phase protein secreted by activated astrocytes or neutrophils, has been shown to promote neuronal ferroptosis via downregulation of SLC7A11 in various CNS disease models, including epilepsy and diabetes-associated ischemic stroke (Zhou Z

Protects against oxidative stress and free radicals

Discussion Bioactive compounds found in nature have great potential for treating diseases and may be safer in than synthetic agents [31, 32]

This highlights the potential of dietary modulation of gut flora to exert neuroprotective effects via metabolic by-products

Glycosphingolipids in neurodegeneration - Molecular mechanisms, cellular roles, and therapeutic perspectives