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The role and therapeutic targeting of JAK/STAT signaling in glioblastoma

[11] In practice, this means that while normal doses are safe, any use of pyridoxine beyond typical supplemental levels during pregnancy should be guided by a healthcare providers assessment of risk versus benefit

Rev Neurosci 10(2):141149

First, the risk profile of patients enrolled in the RCTs does not necessarily match that of patients for whom we are considering weighing the long-term benefits and potential harms