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The release of oxidized phospholipids and their breakdown products acts as danger signals that activate inflammatory pathways

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Because histamine in plasma is rapidly metabolized (~5 minutes) 37 , we assume that plasma histamine levels at steady state largely reflects constitutive release of histamine from tissue mast cells into the circulation

In the meantime, vitamin B12-fortified foods and supplements remain the most reliable source of vitamin B12 for vegetarians and vegans