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The activity of 3-HSD1 was evaluated by monitoring the conversion of pregnenolone to progesterone, a process that involves the reduction of NAD + to NADH

[17] They named it "lymphadenopathy-associated virus", or LAV, since it was not then clear that it was the cause of AIDS, and published their findings in the journal Science on 20 May 1983

For example, the Y390-containing loop is positioned in a manner similar to our original SCF FBXO22 structure with UNC10088 C and NSD2 versus the BACH1-bound structure, suggesting that the two regions function independently to recruit substrates with minimal interference

Matrix Biol (2010) 29(6):5118

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