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In clinical studies, many participants lost between 15% and 20% after 72 weeks of treatment alongside healthy eating and regular activity

In these cases, providers may recommend treatment options that bypass the digestive absorption process

Indeed, high reductive stress can paradoxically elevate superoxide levels via Glutathione Reductase (GSR) and Thioredoxin Reductase (TrxR) due to impaired electron flow caused by inhibitors (65)