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Disclosure of interest: Nothing to disclose Poster session I - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.01 - DIAGNOSIS/INVESTIGATION OF STROKE ETIOLOGY P355 - ESOC25-189 VESSEL WALL ENHANCEMENT IN TERMINAL OF INTERNAL CAROTID ARTERY WAS DECREASED AFTER DIRECT BYPASS SURGERY FOR MOYAMOYA DISEASE Daizo Ishii 1 , Takeshi Hara 1 , Masashi Kuwabara 1 , Hiroshi Kondo 1 , Shinji Kume 2 , Nobutaka Horie 1 1 Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, 2 Hiroshima University Hospital, Hiroshima, Japan Background and Aims: Intracranial vessel wall enhancement (VWE) on MR imaging is associated with progression and poor outcome in moyamoya disease (MMD)

doi: 10.1097/MED.0b013e328013da5b

Bone Tissue: Bone healing is facilitated by stimulation of osteoblast activity and improved callus formation

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2.1.4.1 The engineering continuum: coupling constraint to functional agnosticism Virus-like particle functionalization strategies can be conceptualized along a continuum defined by the degree of thermodynamic coupling between scaffold assembly and antigen incorporation: Genetic fusion (the fully coupled regime): this remains the most structurally deterministic strategy, ensuring strict 1:1 stoichiometry and genetic stability