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The genomics data for endogenous full-length ASXL1, BRD4 and BAP1, and for GFP-ASXL1 1-645 -WT, GFP-ASXL1 1-645 -I574D, BRD4 in GFP-ASXL1 1-645 -WT and BRD4 in GFP-ASXL1 1-645 -I574D generated in this study have been deposited in the Gene Expression Omnibus database under accession code GSE302969

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Microdosing semaglutide simply reduces GLP-1 activation proportionally, while microdosing tirzepatide disproportionately reduces the GLP-1 component while relatively preserving the GIP component

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