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Description

Additional IGF-1 is generated within target tissues, making it what appears to be both an endocrine and an autocrine/paracrine hormone

The same pattern was observed with GM-CSF, with reduced levels in the symptomatic group compared to the asymptomatic group (respectively, 0.9943 0.9730 pg mg protein -1 and 1.870 1.057 pg mg protein -1

RCT: NAC Augmentation of Clozapine Neill et al 11 described an investigator-initiated, industry-independent, moderately large (n = 84), well-designed, well-conducted, well-analyzed, 52-week RCT of NAC (2 g/d) in schizophrenia patients with persistent symptoms that were refractory to at least 3 classes of antipsychotic drugs as well as to 6 months of treatment with their current medication, clozapine