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Therefore, while SOD and CAT are considered promising oxidative stress biomarkers for MASLD, standardized protocols and longitudinal studies are needed to clarify their clinical relevance [168, 169]

34 ChenJ.-Q.RussoJ

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RNA samples were further processed for mRNA-seq library preparation according to the manufacturers instructions (TruSeq RNA Sample preparation v2, Illumina, San Diego, CA, USA)

As a result, the central nervous system becomes hyper-reactive, amplifying normal sensory inputs into severe, nociplastic pain