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The ALOX family can mediate PUFAs peroxidation to generate AA/AdA-PE-OOHs, thereby triggering ferroptosis (Lei et al., 2019)

Seifikalhor M, Aliniaeifard S, Shomali A et al (2019) Calcium signaling and salt tolerance are diversely entwined in plants

During the onset of AD, particularly in the acute phase, changes in the skin barrier activate a Th2-mediated immune response

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Altogether, this second hit, comprising NS3hSL1NS5B, may represent a priming complex, in which interactions between the three partners would position the 3end of the (+) strand to be presented to the RNA binding groove of NS5B (Fig