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Hypothyroidism remains often undiagnosed for a longer period [47] leading to disturbed oxidative balance of prolonged duration, which may cause more lasting changes in fibrinogen function that could be observed after 3 months

Intracellular ROS measurement LNCaP cells were seeded at 6 10 4 cells/well in 24-well plates, adhered overnight and then incubated with conditioned media for 2.5 days before treatment with doxorubicin or taxol

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(PubMed) Traber MG, Leonard SW, Bobe G, et al